Animal models of food allergy (ImpARAS)

3rd Training School

5th -7th June 2018

Medical University of Vienna
Waehringer Guertel 18-20
Vienna, Austria 1090

Call open from March 1st- May 1st, 2018

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Program

ESRs will be trained on animal models of food allergy

Theory:

■ Approaches to experimental animal models of food allergy
■ An overview of all the parameters that need to be considered when designing an animal study with a special focus on novel food
■ Rules of authorization for projects and personnel, 3Rs & recommendations for procedures
■ An example on how we design an animal model for test of a set of “novel” proteins /allergens
■ Approach to sensitization of animals to food allergens including gastrointestinal, respiratory and skin routes
■ Approaches to handling tissues for ex vivo assessment
■ Overview of key cells implicated in food allergy; Characterizing DC, T and B cell in food allergy; Microbiome, innate cell evaluation
■ Protein allergen purification and characterization

Hands-on:

■ Approaches to sensitization in animal models of food allergy
■ Collection and preparation of tissues, organs and cells for the assessment of food allergy
■ Functional exploration of measurement of transit time of food proteins, in vivo permeability, ear swelling, behavior, and temperature drop after challenge
■ A complete dissection of a rat for food allergy research
■ Complete dissection of mice with harvesting of organs

ImpARAS Trainers:

■ Karine Adel-Patient (INRA (National Institute for Agronomic Research))
■ Katrine Lindholm Bøgh (National Food Institute, Technical University of Denmark)
■ Grégory Bouchaud (INRA (National Institute for Agronomic Research))
■ Michelle Epstein (Medical University of Vienna)
■ Karin Hoffmann-Sommergruber (Medical University of Vienna)
■ Liam O’Mahony (SIAF (Swiss Institute of Allergy and Asthma Research))
■ Eva Untersmayr (Medical University of Vienna)

Objective of the Training school

To introduce the use of mouse and rat models for food allergy

Overview of Program

Organizers:  Michelle Epstein, Eva Untersmayr

For more information send an e-mail to: marloes.vanderwal@tno.nl, michelle.epstein@meduniwien.ac.at, eva.untersmayr@meduniwien.ac.at

Practical info

Dates and location:  June 5– 7, 2018 
Experimental Allergy Laboratories, Medical University of Vienna, Austria

Travel grants: 12 travel grants available for meal and accommodation expenses

Registration open: March 1st, 2018

Registration deadline: May 1st, 2018

Acceptance letter to selected applicants:  Mid-May 2018